TO ACTIVATE STEM CELLS IS TO RESTORE VITALITY
As medicine is becoming more and more developed today, the clinical application of stem cell technology represents a major direction for future medical development. More and more people are beginning to come into contact with the term stem cells, but how the public should understand the concept of stem cells and how to benefit from the functions of stem cells, I hope to find the answer in this text .
What are stem cells? What is vitality?
The human body has about 50-70 trillion cells, but every day 1-2% of the cells die and 1-2% of the cells are reborn. The human body needs to constantly produce new cells to replace aging and diseased cells, and new cells are differentiated from stem cells. Stem cells are primitive cells that form various tissues and organs of the human body. They have high potentials of self-replication, directional differentiation, self-renewal, and self-homing, and therefore have the function of repairing the aging tissue systems and organs of the human body.
Stem cells can be divided into two categories according to the different stages of embryonic development:
Embryonic stem cells: Also known as totipotent stem cells, as the name suggests, they are stem cells that can differentiate into all cell types in the human body. The fertilized egg is a typical totipotent stem cell. Because it can differentiate into all cell types in the human body, it has an extremely broad prospect in the treatment of human diseases. However, embryonic stem cells have caused too many ethical and legal controversies, so many researches cannot be carried out.
Adult stem cells: refer to undifferentiated cells that exist in differentiated tissues, which can self-renew and differentiate to form cells that make up this type of tissue, and can also form other types of cells under certain conditions. It exists in the blood and mature tissues of children and adults. At present, adult tissues containing stem cells have been reported as: brain, spinal cord, peripheral blood, blood vessels, skeletal muscle, myocardium, skin, liver, digestive tract and lungs.
The concept of vitality
The concept of vitality formed by the Chinese for thousands of years is:
" Vital energy" is also called innate qi, ancestral qi, true qi, and righteous qi. It is endowed with innateness, and its main reservoir is in the kidneys and life gates. It has the function of the original power of life activities. There are innate qi and acquired qi in the
human body. Acquired qi includes breathing qi and water and valley qi, which are needed to maintain the body's material needs; including Zongqi, Yingqi and Weiqi, which are needed to maintain the body's physiological activities. , There are liver qi, lung qi, heart qi, temper, kidney qi and so on.
The ancestors believed that the acquired qi needed for the physiological activities of various tissues and organs in the body were all separate bodies of innate qi. Qing Xu Lingtai said, "The five internal organs have the essence of the five internal organs, and this division of vitality is also, and its root lies in the so-called dantian in the "Tao Sutra" and the so-called life gate in the "Difficult Sutra"."
Stem cell function and vitality function concept consistency
From a child to adulthood, as the cell proliferation and differentiation ability increases year by year, from 25 to 30 years old, the stem cell proliferation and differentiation ability gradually decreases, and the number of new cells decreases and is less than the dead cells. If the cells are not replaced in time, the body begins to age. Therefore, activating the proliferation and differentiation ability of stem cells is the key to maintaining the functions of various human systems.
According to the "Essence-Qi God Theory" of the Chinese Taoist Life-nourishing Technique, when a baby is born, the nine orifices are energized, and the body's tissues and organs are gradually formed and work normally, the vitality not only completes its original power role, while enjoying the nourishment of the day after tomorrow, To save the kidney and life gate, separate the tissues and organs, and wait still. Once activated by the cultivator, as the cultivator continues to practice, the vitality in his body will continue to be filled, and it will re-order the acquired vitality in the body with the activated "primordial essence" and "primordial spirit" in the body to repair the body , Longevity and longevity.
The view of modern stem cells is fully in line with the concept of vitality of Chinese ancestors .
The function of stem cells in healthcare
Immunomodulatory function:
As a member of the stem cell family, the most important characteristic of mesenchymal stem cells is that they have a strong immunomodulatory effect. Related studies have shown that mesenchymal stem cells that enter the human body can significantly alleviate the condition of patients with liver cirrhosis and significantly reduce the inflammatory response in the liver.
In fact, in the pathogenesis of most serious human diseases, such as liver cirrhosis, diabetes, and even cancer, inflammation plays a vital role. On the other hand, mesenchymal stem cells can change their properties and perform different functions according to the intensity of inflammation or the location of inflammation. When the inflammatory response is strengthened, it can suppress the immune response; when the inflammatory response is weakened, it can promote the immune response.
Reverse cardiac aging:
With the increase of age, the possibility of human cardiovascular diseases increases. Cellular aging is the main cause of the aging process of the heart, which is characterized by shortened telomeres, the ends of chromosomes. Telomere shortening is related to cardiac dysfunction and hypertrophy, the proliferation of cardiomyocytes is impaired, and the interstitial fibrosis results in the decline of regeneration ability.
Research on injecting cardiac stem cells into the heart can help reverse the natural cardiac aging process has been carried out. It is believed that similar treatments can be used one day to prevent age-related cardiac function decline and cardiovascular diseases in humans.
Ischemic disease:
Studies have shown that adipose stem cells can secrete a certain amount of cytokines, such as vascular growth factors VEGF, PDGF, bFGF, angiopoietin, GM-CSF, MCP-1 and SDF-1α, and these factors are conducive to the establishment of better damage Repair the environment. Among them, platelet-derived endothelial cell growth factor has been proven to promote angiogenesis in vivo and in vitro. This feature has further expanded the application prospects of adipose stem cells in clinical treatment.
For example, acute myocardial infarction, ischemic cardiomyopathy, peripheral vascular disease, acute tubular necrosis, diabetic retinopathy, ischemic encephalopathy, traumatic spinal cord injury, and ischemia during transplantation.
Repair central nervous system damage:
The application of various types of nerve cells derived from neural stem cells is mainly focused on repairing the damaged central nervous system.
In a phase I clinical study conducted by ReNeuron, immortalized human fetal neuron stem cells were transplanted into 11 stroke patients, followed by 12 months of follow-up observation, and no cell-related or immune-related problems were found. Harmful effects, these immortalized neural stem cells will not occupy the brain tissue, they are just a group of transient cell populations. At present, researchers have observed some improvement in the condition in this study. Phase II clinical trials are ongoing to evaluate transplantation. The benefits of neuronal stem cells for stroke patients.
In addition, neuronal stem cells have also carried out relevant research on the treatment of amyotrophic lateral sclerosis, spinal cord injury, retinopathy, and brain glioblastoma.
Tumor:
Recombinant interferon α (IFNα) can be used as a clinical drug to treat a variety of tumors, but due to its short half-life, high dosage, and serious side effects, its clinical application is limited. To solve this bottleneck problem, scientists use the carrier function of mesenchymal stem cells to carry and express IFNα to achieve local release of the cytokine and targeted tumor therapy. Experiments have found that the anti-tumor ability of mesenchymal stem cells that can secrete IFNα is significantly higher than that of IFNα recombinant protein.
From the above stem cell application research , we can summarize three characteristics of stem cells:
- Adults generally 95% or more of the stem cells in a resting state is not active, it must be, as in the activator occurs when tissues are damaged injuries when issued a distress signal , the stem cells only wake up began to proliferate.
- It can migrate to target tissues on its own, such as immunomodulation and targeted therapy of tumors.
- According to the needs of the body, stem cells can differentiate into different functional cells according to developmental pathways.
Cosmetic surgery:
- There are many reports on the application of adipose stem cells in cosmetic and plastic surgery, and their clinical effects are also the most significant. It has been very mature in the application of wrinkle removal, whitening, breast enhancement, butt lift and other cosmetic and plastic fields. At the same time, its application and research in anti-aging are also underway.
This shows that the role of stem cells in the human body is very important. If the human body is compared to a machine, and organs and tissues are compared to parts, stem cells are the parts production base. Whatever breaks down, replace it! Although immortality is unlikely, but to help people stay away from illness and maintain youthful vitality, stem cells can still carry It's a big responsibility!
Regular activation of stem cells is the way to restore vitality
The human body has five plagues and six diseases, emotional pressure, and age factors, which lead to poor health. According to the principle of " boiling frogs in warm water " , as the age increases, the response of human stem cells to the distress factors of various systems will gradually slow down. Therefore, activating human stem cells on a regular basis is tantamount to stem cell exercises and military training, and is the only way to restore the body's vitality.
The bigu method invented by Chinese ancestors and the retreats of martial arts masters were artificially caused by the body to feel a crisis, mobilizing all stem cells to activate, thereby restoring vitality and increasing power.
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The important concept is said three times: to activate stem cells is to restore the body's vitality! To activate stem cells is to restore the body's vitality! To activate stem cells is to restore the body's vitality!
达玛烷皂苷RG1 和 RB1
大量的科学研究表明,人参总皂苷内的达玛烷皂苷Rg1具有无毒高效的刺激干细胞的作用,能够:刺激造血干细胞增殖,促进造血和免疫促进神经元干细胞增殖,恢复大脑活力刺激内皮祖细胞改善内皮功能,恢复血管健康诱导间充质干细胞分化,维护脏器健康。
因此,达玛烷皂苷Rg1、Re和Rb1的刺激干细胞作用能够改善或延缓衰老带来的一系列病理和生理变化:
(1)脱发、皮肤松弛、色素沉着:这些变化大多是由于皮肤细胞活力减退所致。通过刺激皮肤内的干细胞,从而增加毛囊活性,刺激皮肤内胶原蛋白产生和色素清除,从而恢复皮肤健康。
(2)代谢综合征:患者通常表现为肥胖、高血脂、糖耐量异常或糖尿病、高血压、痛风等。这是由于相关的脂肪细胞、骨骼肌细胞、内皮细胞的活力丧失所致。Rg1能够促进间充质干细胞变成和替代这些细胞,从而恢复对脂肪的代谢,增加胰岛素敏感性,降低血糖、血压等。
(3)老年性神经退行性疾病:常见的帕金森氏病和阿尔茨海默病(Alzheimer’s Disease)。这些疾病使得老年人智力和活动能力下降、生活自理能力降低或丧失,给社会和家庭带来极大的负担。Rg1能够明显刺激神经干细胞,产生新的有活力的神经元细胞,从而阻止或延缓疾病的发展。
(4)疾病后遗症:中风和心肌梗塞等。心血管疾病是中老年人的常见疾病,其严重的并发症可以导致病人寿命减少,生活质量降低。Rg1能够促进干细胞修复受损的组织和脏器,从而减轻后遗症的症状,从而改善病人生活质量和延长寿命。
